• Nervous System Support
• Supports Emotional Well-Being
• Supports Joint Health
• Enteric Coated
• New Oval Tablet
• Enteric Coated
• A Dietary Supplement
• Vegetarian/Vegan
• Kosher
• Amino Acids
• Family Owned Since 1968
• GMP Quality Assured

SAMe (S-adenosylmethionine), a compound native to the body, is a component of many biochemical reactions, including those that affect brain biochemistry and joint health. Numerous studies have indicated that SAMe can help to alleviate transient minor aches and pains resulting from overexertion or strain. In addition, because SAMe is also necessary for the synthesis of neurotransmitters, it plays an important role in mood support. NOW® SAMe is enteric-coated, which makes it very well tolerated and protects it from degradation.

Take 1 tablet 2 to 4 times daily, preferably on an empty stomach.

Microcrystalline cellulose, enteric coating (methacrylic acid, hypromellose, calcium carbonate, hydroxypropyl cellulose, glycerin), croscarmellose sodium, magnesium stearate (vegetable source), silicon dioxide, stearic acid (vegetable source), ascorbic acid and citric acid. 

Not manufactured with wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Natural color variation may occur in this product.

For adults only. Individuals with bipolar depression, anxiety disorders or taking antidepressant medications should not take SAMe unless under professional medical supervision. Consult physician if pregnant/nursing, taking medication, or have a medical condition. Keep out of reach of children.

While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.